Author Correction: Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21

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This pattern has caused connection pool exhaustion in Node.js applications using undici (the fetch() implementation built into Node.js), and similar issues have appeared in other runtimes. The stream holds a reference to the underlying connection, and without explicit consumption or cancellation, the connection may linger until garbage collection — which may not happen soon enough under load.